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NPAS1 Represses the Generation of Specific Subtypes of Cortical Interneurons

Little is known about genetic mechanisms that regulate the ratio of cortical excitatory and inhibitory neurons. We show that NPAS1 and NPAS3 transcription factors (TF) are expressed in progenitor domains of the mouse basal ganglia (subpallium, MGE and CGE). NPAS1(−/−) mutants had increased prolifera...

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發表在:Neuron
Main Authors: Stanco, Amelia, Pla, Ramón, Vogt, Daniel, Chen, Yiran, Mandal, Shyamali, Walker, Jamie, Hunt, Robert F., Lindtner, Susan, Erdman, Carolyn A., Pieper, Andrew A., Hamilton, Steven P., Xu, Duan, Baraban, Scott C., Rubenstein, John L. R.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258152/
https://ncbi.nlm.nih.gov/pubmed/25467980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.10.040
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