PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T cell infiltration into pancreatic tumors

Pancreatic ductal adenocarcinoma (PDA) has a poor prognosis due to late detection and resistance to conventional therapies. Published studies show that the PDA tumor microenvironment (TME) is predominantly infiltrated with immune suppressive cells and signals that if altered, would allow effective i...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Immunother
Κύριοι συγγραφείς: Soares, Kevin C., Rucki, Agnieszka A., Wu, Annie A., Olino, Kelly, Xiao, Qian, Chai, Yi, Wamwea, Anthony, Bigelow, Elaine, Lutz, Eric, Liu, Linda, Yao, Sheng, Anders, Robert A., Laheru, Daniel, Wolfgang, Christopher L., Edil, Barish H., Schulick, Richard D., Jaffee, Elizabeth M., Zheng, Lei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258151/
https://ncbi.nlm.nih.gov/pubmed/25415283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000062
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