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Post-Exposure Administration of Diazepam Combined with Soluble Epoxide Hydrolase Inhibition Stops Seizures and Modulates Neuroinflammation in a Murine Model of Acute TETS Intoxication
Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison for which there is currently no approved antidote. The convulsant action of TETS is thought to be mediated by inhibition of type A gamma-aminobutyric acid receptor (GABA(A)R) function. We, therefore, investigated the effects of post...
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| 出版年: | Toxicol Appl Pharmacol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258121/ https://ncbi.nlm.nih.gov/pubmed/25448683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.10.001 |
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