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Inhibition of soluble epoxide hydrolase as a novel approach to high dose diazepam induced hypotension

CONTEXT: Hypotension is one of the dose limiting side effects of benzodiazepines (BZDs), in particular of diazepam (DZP) which is still widely used in the clinic. Currently, only one FDA approved antidote exists for BZD overdose and novel approaches are needed to improve management of DZP overdose,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Toxicol
Prif Awduron: Ulu, Arzu, Inceoglu, Bora, Yang, Jun, Singh, Vikrant, Vito, Stephen, Wulff, Heike, Hammock, Bruce D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328659/
https://ncbi.nlm.nih.gov/pubmed/28255523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0495.1000300
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