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Post-Exposure Administration of Diazepam Combined with Soluble Epoxide Hydrolase Inhibition Stops Seizures and Modulates Neuroinflammation in a Murine Model of Acute TETS Intoxication

Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison for which there is currently no approved antidote. The convulsant action of TETS is thought to be mediated by inhibition of type A gamma-aminobutyric acid receptor (GABA(A)R) function. We, therefore, investigated the effects of post...

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محفوظ في:

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Toxicol Appl Pharmacol
المؤلفون الرئيسيون:	Vito, Stephen T., Austin, Adam T., Banks, Christopher N., Inceoglu, Bora, Bruun, Donald A., Zolkowska, Dorota, Tancredi, Daniel J., Rogawski, Michael A., Hammock, Bruce D., Lein, Pamela J.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2014
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4258121/ https://ncbi.nlm.nih.gov/pubmed/25448683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.10.001
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Post-Exposure Administration of Diazepam Combined with Soluble Epoxide Hydrolase Inhibition Stops Seizures and Modulates Neuroinflammation in a Murine Model of Acute TETS Intoxication

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