Opposing mechanisms of regulation of a G-protein-coupled inward rectifier K+ channel in rat brain neurons.

In locus coeruleus neurons, substance P (SP) suppresses an inwardly rectifying K+ current via a pertussis toxin-insensitive guanine nucleotide binding protein (G protein; GnonPTX), whereas somatostatin (SOM) or [Met]enkephalin (MENK) enhances it via a pertussis toxin-sensitive G protein (GPTX). The...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Velimirovic, B M, Koyano, K, Nakajima, S, Nakajima, Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7533296/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1590
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