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Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol

Abstract Activation of G protein-gated inwardly rectifying potassium (GIRK) channels leads to a hyperpolarization of the neuron’s membrane potential, providing an important component of inhibition in the brain. In addition to the canonical G protein-activation pathway, GIRK channels are activated by...

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Hlavní autoři: Ian W. Glaaser, Paul A. Slesinger
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2017-07-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-017-04681-x
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