Aminoglycoside Stress Together with the 12S rRNA 1494C>T Mutation Leads to Mitophagy

Aminoglycosides as modifying factors modulated the phenotypic manifestation of mitochondrial rRNA mutations and the incomplete penetrance of hearing loss. In this report, using cybrids harboring the m.1494C>T mutation, we showed that gentamycin aggravated mitochondrial dysfunction in a combinatio...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Yu, Jialing, Zheng, Jing, Zhao, Xiaoxu, Liu, Junxia, Mao, Zhuochao, Ling, Yining, Chen, Danni, Chen, Chao, Hui, Lanlan, Cui, Limei, Chen, Ye, Jiang, Pingping, Guan, Min-Xin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256443/
https://ncbi.nlm.nih.gov/pubmed/25474306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114650
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