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Interaction of Aminoglycosides with Human Mitochondrial 12S rRNA Carrying the Deafness-Associated Mutation

The mitochondrial 12S rRNA A1555G mutation is one of the important causes of aminoglycoside-induced and nonsyndromic hearing loss. Here we employed an RNA-directed chemical-modification approach to understanding the pathogenesis of aminoglycoside-induced hearing loss. The patterns of chemical modifi...

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Bibliografiska uppgifter
Huvudupphovsmän: Qian, Yaping, Guan, Min-Xin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772318/
https://ncbi.nlm.nih.gov/pubmed/19687236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00965-08
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