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Functional characterization of the mitochondrial 12S rRNA C1494T mutation associated with aminoglycoside-induced and non-syndromic hearing loss

In this study, we report the biochemical characterization of the deafness-associated mitochondrial 12S rRNA C1494T mutation using 27 cybrid cell lines constructed by transferring mitochondria from 9 lymphoblastoid cell lines derived from a Chinese family into human mitochondrial DNA (mtDNA)-less (ρ°...

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Библиографические подробности
Главные авторы: Zhao, Hui, Young, Wie-Yen, Yan, Qingfeng, Li, Ronghua, Cao, Juyang, Wang, Qiuju, Li, Xiaoming, Peters, Jennifer L., Han, Dongyi, Guan, Min-Xin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2005
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC549421/
https://ncbi.nlm.nih.gov/pubmed/15722487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki262
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