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Proteinase-activated Receptor 2 (PAR2) Decreases Apoptosis in Colonic Epithelial Cells

Mucosal biopsies from inflamed colon of inflammatory bowel disease patients exhibit elevated epithelial apoptosis compared with those from healthy individuals, disrupting mucosal homeostasis and perpetuating disease. Therapies that decrease intestinal epithelial apoptosis may, therefore, ameliorate...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Iablokov, Vadim, Hirota, Christina L., Peplowski, Michael A., Ramachandran, Rithwik, Mihara, Koichiro, Hollenberg, Morley D., MacNaughton, Wallace K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256365/
https://ncbi.nlm.nih.gov/pubmed/25331954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610485
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