Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways

BACKGROUND AND PURPOSE: Because angiotensin-II-mediated porcine coronary artery (PCA) vasoconstriction is blocked by protein tyrosine kinase (PYK) inhibitors, we hypothesized that proteinase-activated receptors (PARs), known to regulate vascular tension, like angiotensin-II, would also cause PCA con...

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Main Authors: El-Daly, Mahmoud, Saifeddine, Mahmoud, Mihara, Koichiro, Ramachandran, Rithwik, Triggle, Christopher R, Hollenberg, Morley D
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997280/
https://ncbi.nlm.nih.gov/pubmed/24506284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12593
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