Tumor necrosis factor α decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription

Inflammatory diseases of the gut are associated with altered electrolyte and water transport, leading to the development of diarrhea. Epithelially expressed aquaporins (AQPs) are downregulated in inflammation, although the mechanisms involved are not known. We hypothesized that AQP3 expression in in...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Peplowski, Michael A., Vegso, Andrew J., Iablokov, Vadim, Dicay, Michael, Zaheer, Raza S., Renaux, Bernard, Proud, David, Hollenberg, Morley D., Beck, Paul L., MacNaughton, Wallace K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641937/
https://ncbi.nlm.nih.gov/pubmed/29038361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13451
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