Tumor necrosis factor α decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription

Inflammatory diseases of the gut are associated with altered electrolyte and water transport, leading to the development of diarrhea. Epithelially expressed aquaporins (AQPs) are downregulated in inflammation, although the mechanisms involved are not known. We hypothesized that AQP3 expression in in...

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Библиографические подробности
Опубликовано в: :Physiol Rep
Главные авторы: Peplowski, Michael A., Vegso, Andrew J., Iablokov, Vadim, Dicay, Michael, Zaheer, Raza S., Renaux, Bernard, Proud, David, Hollenberg, Morley D., Beck, Paul L., MacNaughton, Wallace K.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641937/
https://ncbi.nlm.nih.gov/pubmed/29038361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13451
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