The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction

Barrier dysfunction is a characteristic of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Understanding how the tight junction is modified to maintain barrier function may provide avenues for treatment of IBD. We have previously shown that the apical addition of...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Ronaghan, Natalie J., Shang, Judie, Iablokov, Vadim, Zaheer, Raza, Colarusso, Pina, Dion, Sébastien, Désilets, Antoine, Leduc, Richard, Turner, Jerrold R., MacNaughton, Wallace K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Epithelial Biology and Secretion
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076006/
https://ncbi.nlm.nih.gov/pubmed/27492333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00441.2015
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