The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction

Barrier dysfunction is a characteristic of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Understanding how the tight junction is modified to maintain barrier function may provide avenues for treatment of IBD. We have previously shown that the apical addition of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Gastrointest Liver Physiol
Prif Awduron: Ronaghan, Natalie J., Shang, Judie, Iablokov, Vadim, Zaheer, Raza, Colarusso, Pina, Dion, Sébastien, Désilets, Antoine, Leduc, Richard, Turner, Jerrold R., MacNaughton, Wallace K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2016
Pynciau:
Epithelial Biology and Secretion
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076006/
https://ncbi.nlm.nih.gov/pubmed/27492333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00441.2015
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