The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction

Barrier dysfunction is a characteristic of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Understanding how the tight junction is modified to maintain barrier function may provide avenues for treatment of IBD. We have previously shown that the apical addition of...

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Dettagli Bibliografici
Pubblicato in:Am J Physiol Gastrointest Liver Physiol
Autori principali: Ronaghan, Natalie J., Shang, Judie, Iablokov, Vadim, Zaheer, Raza, Colarusso, Pina, Dion, Sébastien, Désilets, Antoine, Leduc, Richard, Turner, Jerrold R., MacNaughton, Wallace K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
Soggetti:
Epithelial Biology and Secretion
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076006/
https://ncbi.nlm.nih.gov/pubmed/27492333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00441.2015
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