The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation

We have previously shown that the L-type calcium channel (LCC) antagonist nilvadipine reduces brain amyloid-β (Aβ) accumulation by affecting both Aβ production and Aβ clearance across the blood-brain barrier (BBB). Nilvadipine consists of a mixture of two enantiomers, (+)-nilvadipine and (−)-nilvadi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Paris, Daniel, Ait-Ghezala, Ghania, Bachmeier, Corbin, Laco, Gary, Beaulieu-Abdelahad, David, Lin, Yong, Jin, Chao, Crawford, Fiona, Mullan, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256331/
https://ncbi.nlm.nih.gov/pubmed/25331948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608091
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker