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Enhancement of Flow-Induced AP-1 Gene Expression by Cyclosporin A Requires NFAT-Independent Signaling in Bone Cells

Growing evidence suggests that aging compromises the ability of the skeleton to respond to anabolic mechanical stimuli. Recently, we reported that treating senescent mice with Cyclosporin A (CsA) rescued aging-related deficits in loading-induced bone formation. Given that the actions of CsA are ofte...

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Bibliografische gegevens
Gepubliceerd in:Cell Mol Bioeng
Hoofdauteurs: WORTON, LEAH E., KWON, RONALD Y., GARDINER, EDITH M., GROSS, TED S., SRINIVASAN, SUNDAR
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255985/
https://ncbi.nlm.nih.gov/pubmed/25484988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-014-0321-3
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