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Enhancement of Flow-Induced AP-1 Gene Expression by Cyclosporin A Requires NFAT-Independent Signaling in Bone Cells

Growing evidence suggests that aging compromises the ability of the skeleton to respond to anabolic mechanical stimuli. Recently, we reported that treating senescent mice with Cyclosporin A (CsA) rescued aging-related deficits in loading-induced bone formation. Given that the actions of CsA are ofte...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: WORTON, LEAH E., KWON, RONALD Y., GARDINER, EDITH M., GROSS, TED S., SRINIVASAN, SUNDAR
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255985/
https://ncbi.nlm.nih.gov/pubmed/25484988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-014-0321-3
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