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Enhancement of Flow-Induced AP-1 Gene Expression by Cyclosporin A Requires NFAT-Independent Signaling in Bone Cells

Growing evidence suggests that aging compromises the ability of the skeleton to respond to anabolic mechanical stimuli. Recently, we reported that treating senescent mice with Cyclosporin A (CsA) rescued aging-related deficits in loading-induced bone formation. Given that the actions of CsA are ofte...

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Foilsithe in:Cell Mol Bioeng
Main Authors: WORTON, LEAH E., KWON, RONALD Y., GARDINER, EDITH M., GROSS, TED S., SRINIVASAN, SUNDAR
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255985/
https://ncbi.nlm.nih.gov/pubmed/25484988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-014-0321-3
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