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Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death

Protein homeostatic regulators have been shown to ameliorate single, loss-of-function protein diseases but not to treat broader animal disease models that may involve cell death. Diseases often trigger protein homeostatic instability that disrupts the delicate balance of normal cellular viability. F...

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書目詳細資料
發表在:Cell Stress Chaperones
Main Authors: Sharma, Sudhish, Mishra, Rachana, Walker, Brandon L., Deshmukh, Savitha, Zampino, Manuela, Patel, Jay, Anamalai, Mani, Simpson, David, Singh, Ishwar S., Kaushal, Shalesh, Kaushal, Sunjay
格式: Artigo
語言:Inglês
出版: Springer Netherlands 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255245/
https://ncbi.nlm.nih.gov/pubmed/25300203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0536-1
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