Cardiosphere Derived Cells from Pediatric End-Stage Heart Failure Patients Have Enhanced Functional Activity due to the Heat Shock Response Regulating the Secretome

We have demonstrated that human neonatal cardiosphere derived cells (CDCs) derived from the young are more regenerative due to their robust secretome. However, it is unclear how the decompensated pediatric heart impacts the functional activity of their CDCs. Our aim was to characterize the potency o...

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Bibliografiska uppgifter
I publikationen:Stem Cells
Huvudupphovsmän: Sharma, Sudhish, Mishra, Rachana, Simpson, David, Wehman, Brody, Colletti, Evan J., Deshmukh, Savitha, Datla, Srinivasa Raju, Balachandran, Keerti, Guo, Yin, Chen, Ling, Siddiqui, Osama T., Kaushal, Shalesh, Kaushal, Sunjay
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801025/
https://ncbi.nlm.nih.gov/pubmed/25752510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1937
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