Cardiosphere Derived Cells from Pediatric End-Stage Heart Failure Patients Have Enhanced Functional Activity due to the Heat Shock Response Regulating the Secretome

We have demonstrated that human neonatal cardiosphere derived cells (CDCs) derived from the young are more regenerative due to their robust secretome. However, it is unclear how the decompensated pediatric heart impacts the functional activity of their CDCs. Our aim was to characterize the potency o...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: Sharma, Sudhish, Mishra, Rachana, Simpson, David, Wehman, Brody, Colletti, Evan J., Deshmukh, Savitha, Datla, Srinivasa Raju, Balachandran, Keerti, Guo, Yin, Chen, Ling, Siddiqui, Osama T., Kaushal, Shalesh, Kaushal, Sunjay
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801025/
https://ncbi.nlm.nih.gov/pubmed/25752510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1937
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