Cardiosphere Derived Cells from Pediatric End-Stage Heart Failure Patients Have Enhanced Functional Activity due to the Heat Shock Response Regulating the Secretome

We have demonstrated that human neonatal cardiosphere derived cells (CDCs) derived from the young are more regenerative due to their robust secretome. However, it is unclear how the decompensated pediatric heart impacts the functional activity of their CDCs. Our aim was to characterize the potency o...

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Publicado en:Stem Cells
Autores principales: Sharma, Sudhish, Mishra, Rachana, Simpson, David, Wehman, Brody, Colletti, Evan J., Deshmukh, Savitha, Datla, Srinivasa Raju, Balachandran, Keerti, Guo, Yin, Chen, Ling, Siddiqui, Osama T., Kaushal, Shalesh, Kaushal, Sunjay
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801025/
https://ncbi.nlm.nih.gov/pubmed/25752510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1937
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