Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death

Protein homeostatic regulators have been shown to ameliorate single, loss-of-function protein diseases but not to treat broader animal disease models that may involve cell death. Diseases often trigger protein homeostatic instability that disrupts the delicate balance of normal cellular viability. F...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stress Chaperones
Prif Awduron: Sharma, Sudhish, Mishra, Rachana, Walker, Brandon L., Deshmukh, Savitha, Zampino, Manuela, Patel, Jay, Anamalai, Mani, Simpson, David, Singh, Ishwar S., Kaushal, Shalesh, Kaushal, Sunjay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2014
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255245/
https://ncbi.nlm.nih.gov/pubmed/25300203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0536-1
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