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Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death

Protein homeostatic regulators have been shown to ameliorate single, loss-of-function protein diseases but not to treat broader animal disease models that may involve cell death. Diseases often trigger protein homeostatic instability that disrupts the delicate balance of normal cellular viability. F...

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Bibliografski detalji
Izdano u:Cell Stress Chaperones
Glavni autori: Sharma, Sudhish, Mishra, Rachana, Walker, Brandon L., Deshmukh, Savitha, Zampino, Manuela, Patel, Jay, Anamalai, Mani, Simpson, David, Singh, Ishwar S., Kaushal, Shalesh, Kaushal, Sunjay
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255245/
https://ncbi.nlm.nih.gov/pubmed/25300203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0536-1
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