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Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor

Membrane proteins, especially G-protein coupled receptors (GPCRs), are interesting and important theragnostic targets since many of them serve in intracellular signaling critical for all aspects of health and disease. The potential utility of designed bivalent ligands as targeting agents for cancer...

詳細記述

保存先:
書誌詳細
出版年:Bioorg Med Chem
主要な著者: Fernandes, Steve M., Lee, Yeon Sun, Gillies, Robert J., Hruby, Victor J.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254589/
https://ncbi.nlm.nih.gov/pubmed/25438759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.055
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