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Synthesis and Evaluation of Bivalent NDP-α-MSH(7) Peptide Ligands for Binding to the Human Melanocortin Receptor 4 (hMC4R)

We demonstrate the potential utility of multivalent ligands as targeting agents for cancer imaging or therapy by determining the binding of homobivalent ligands to their corresponding receptors. This manuscript details the synthesis and evaluation of a series of bivalent ligands containing two copie...

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Detalhes bibliográficos
Main Authors: Handl, Heather L., Sankaranarayanan, Rajesh, Josan, Jatinder S., Vagner, Josef, Mash, Eugene A., Gillies, Robert J., Hruby, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538036/
https://ncbi.nlm.nih.gov/pubmed/17591746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc0603642
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