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Synthesis and Evaluation of Bivalent NDP-α-MSH(7) Peptide Ligands for Binding to the Human Melanocortin Receptor 4 (hMC4R)

We demonstrate the potential utility of multivalent ligands as targeting agents for cancer imaging or therapy by determining the binding of homobivalent ligands to their corresponding receptors. This manuscript details the synthesis and evaluation of a series of bivalent ligands containing two copie...

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Bibliografiske detaljer
Main Authors: Handl, Heather L., Sankaranarayanan, Rajesh, Josan, Jatinder S., Vagner, Josef, Mash, Eugene A., Gillies, Robert J., Hruby, Victor J.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538036/
https://ncbi.nlm.nih.gov/pubmed/17591746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc0603642
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