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Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor
The epidermal growth factor receptor (EGFR) plays pivotal roles in development and is mutated or overexpressed in several cancers. Despite recent advances, the complex allosteric regulation of EGFR remains incompletely understood. In efforts to understand why the negative cooperativity observed for...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254573/ https://ncbi.nlm.nih.gov/pubmed/25453753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.010 |
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