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Putting together structures of epidermal growth factor receptors
Numerous crystal structures have been reported for the isolated extracellular region and tyrosine kinase domain of the epidermal growth factor receptor (EGFR) and its relatives, in different states of activation and bound to a variety of inhibitors used in cancer therapy. The next challenge is to pu...
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| Publicado no: | Curr Opin Struct Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268130/ https://ncbi.nlm.nih.gov/pubmed/25460273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.10.002 |
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