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Putting together structures of epidermal growth factor receptors

Numerous crystal structures have been reported for the isolated extracellular region and tyrosine kinase domain of the epidermal growth factor receptor (EGFR) and its relatives, in different states of activation and bound to a variety of inhibitors used in cancer therapy. The next challenge is to pu...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Curr Opin Struct Biol
Päätekijät: Bessman, Nicholas J., Freed, Daniel M., Lemmon, Mark A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268130/
https://ncbi.nlm.nih.gov/pubmed/25460273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.10.002
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