Structural alterations of the epidermal growth factor receptor gene in human gliomas.

The epidermal growth factor receptor (EGFR) gene is amplified in 40% of malignant gliomas, and the amplified genes are frequently rearranged. We have characterized the genetic alterations associated with these rearrangements in five malignant gliomas. In one tumor the rearrangement resulted in the d...

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Bibliografiska uppgifter
Huvudupphovsmän: Wong, A J, Ruppert, J M, Bigner, S H, Grzeschik, C H, Humphrey, P A, Bigner, D S, Vogelstein, B
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC48784/
https://ncbi.nlm.nih.gov/pubmed/1557402
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