טוען...
TALEN gene knockouts reveal no requirement for the conserved human shelterin protein Rap1 in telomere protection and length regulation
The conserved protein Rap1 functions at telomeres in fungi, protozoa, and vertebrates. Like yeast Rap1, human Rap1 has been implicated in telomere length regulation and repression of non-homologous end joining (NHEJ) at telomeres. However, mouse telomeres lacking Rap1 do not succumb to NHEJ. To dete...
שמור ב:
| הוצא לאור ב: | Cell Rep |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254571/ https://ncbi.nlm.nih.gov/pubmed/25453752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.014 |
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