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Taking apart Rap1: An adaptor protein with telomeric and non-telomeric functions

Mammalian Rap1, a TRF2-interacting protein in the telomeric shelterin complex, was recently shown to repress homology-directed repair at chromosome ends. In addition, Rap1 plays a role in transcriptional regulation and NFκB signaling. Rap1 is unique among the components of shelterin in that it is co...

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Hlavní autoři: Kabir, Shaheen, Sfeir, Agnel, de Lange, Titia
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995270/
https://ncbi.nlm.nih.gov/pubmed/20948311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13579
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