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Taking apart Rap1: An adaptor protein with telomeric and non-telomeric functions
Mammalian Rap1, a TRF2-interacting protein in the telomeric shelterin complex, was recently shown to repress homology-directed repair at chromosome ends. In addition, Rap1 plays a role in transcriptional regulation and NFκB signaling. Rap1 is unique among the components of shelterin in that it is co...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995270/ https://ncbi.nlm.nih.gov/pubmed/20948311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13579 |
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