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Rap1 Affects the Length and Heterogeneity of Human Telomeres

Telomere length is controlled in part by cis-acting negative regulators that limit telomere extension by telomerase. In budding yeast, the major telomere length regulator scRap1 binds to telomeric DNA and acts to inhibit telomere elongation in cis. Because the human Rap1 ortholog hRap1 does not bind...

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Detalhes bibliográficos
Main Authors: Li, Bibo, de Lange, Titia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC284807/
https://ncbi.nlm.nih.gov/pubmed/14565979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-06-0403
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