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Rap1 Affects the Length and Heterogeneity of Human Telomeres
Telomere length is controlled in part by cis-acting negative regulators that limit telomere extension by telomerase. In budding yeast, the major telomere length regulator scRap1 binds to telomeric DNA and acts to inhibit telomere elongation in cis. Because the human Rap1 ortholog hRap1 does not bind...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC284807/ https://ncbi.nlm.nih.gov/pubmed/14565979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-06-0403 |
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