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Rap1 Affects the Length and Heterogeneity of Human Telomeres

Telomere length is controlled in part by cis-acting negative regulators that limit telomere extension by telomerase. In budding yeast, the major telomere length regulator scRap1 binds to telomeric DNA and acts to inhibit telomere elongation in cis. Because the human Rap1 ortholog hRap1 does not bind...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Bibo, de Lange, Titia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC284807/
https://ncbi.nlm.nih.gov/pubmed/14565979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-06-0403
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