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Analysis of Free Drug Fractions by Ultrafast Affinity Extraction: Interactions of Sulfonylurea Drugs with Normal or Glycated Human Serum Albumin

Ultrafast affinity extraction and a multi-dimensional affinity system were developed for measuring free drug fractions at therapeutic levels. This approach was used to compare the free fractions and global affinity constants of several sulfonylurea drugs in the presence of normal human serum albumin...

詳細記述

保存先:
書誌詳細
出版年:J Chromatogr A
主要な著者: Zheng, Xiwei, Matsuda, Ryan, Hage, David S.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254497/
https://ncbi.nlm.nih.gov/pubmed/25456590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2014.10.092
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