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Binding Studies Based on Ultrafast Affinity Extraction and Single- or Two-Column Systems: Interactions of Second- and Third-Generation Sulfonylurea Drugs with Normal or Glycated Human Serum Albumin
Ultrafast affinity extraction was evaluated and used with microcolumns containing human serum albumin (HSA) to measure the global affinity constants and dissociation rate constants for several second- and third-generation sulfonylurea drugs with solution-phase normal HSA or glycated HSA. Glibenclami...
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| Publicado no: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251404/ https://ncbi.nlm.nih.gov/pubmed/30366211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2018.10.015 |
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