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Binding Studies Based on Ultrafast Affinity Extraction and Single- or Two-Column Systems: Interactions of Second- and Third-Generation Sulfonylurea Drugs with Normal or Glycated Human Serum Albumin

Ultrafast affinity extraction was evaluated and used with microcolumns containing human serum albumin (HSA) to measure the global affinity constants and dissociation rate constants for several second- and third-generation sulfonylurea drugs with solution-phase normal HSA or glycated HSA. Glibenclami...

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Détails bibliographiques
Publié dans:J Chromatogr B Analyt Technol Biomed Life Sci
Auteurs principaux: Yang, Bao, Zheng, Xiwei, Hage, David S.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251404/
https://ncbi.nlm.nih.gov/pubmed/30366211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2018.10.015
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