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Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation.

von Willebrand factor (vWF) is necessary for the initial attachment of platelets to exposed subendothelium, particularly under flow conditions like those prevailing in the microcirculation. Little is known about its possible participation in subsequent events leading to formation of platelet thrombi...

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Pubblicato in:J Clin Invest
Autori principali: De Marco, L, Girolami, A, Russell, S, Ruggeri, Z M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3157702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111816
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