Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.

In this study we have used two new monoclonal antibodies, designated LJP5 and LJP9, as well as a previously described one, AP2, all specific for the platelet membrane glycoprotein (GP)IIb/IIIa complex. None of them reacted with dissociated GPIIb or GPIIIa. The monovalent Fab fragment of both LJP5 an...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lombardo, V T, Hodson, E, Roberts, J R, Kunicki, T J, Zimmerman, T S, Ruggeri, Z M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2414325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112193
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