Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa.

We have studied the interaction of the congenitally abnormal type IIA and IIB von Willebrand factor (vWF) molecules, both lacking the larger multimeric forms, with the two vWF binding sites on platelets, the glycoprotein (GP) Ib-IX and GP IIb-IIIa complexes. Variant as well as normal (N) vWF were pu...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: De Marco, L, Mazzucato, M, De Roia, D, Casonato, A, Federici, A B, Girolami, A, Ruggeri, Z M
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1990
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2394830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114775
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