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Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.

The fibrinogen receptor on human platelets is a prototypic member of the integrin family and is composed of subunit glycoproteins IIb (gpIIb) and IIIa (gpIIIa) in a 1:1 stoichiometric ratio. We have isolated cDNA clones for gpIIb and gpIIIa and localized both genes to chromosome 17. In the current s...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Bray, P F, Barsh, G, Rosa, J P, Luo, X Y, Magenis, E, Shuman, M A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8683
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