Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.

The fibrinogen receptor on human platelets is a prototypic member of the integrin family and is composed of subunit glycoproteins IIb (gpIIb) and IIIa (gpIIIa) in a 1:1 stoichiometric ratio. We have isolated cDNA clones for gpIIb and gpIIIa and localized both genes to chromosome 17. In the current s...

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Bibliographic Details
Main Authors: Bray, P F, Barsh, G, Rosa, J P, Luo, X Y, Magenis, E, Shuman, M A
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC282524/
https://ncbi.nlm.nih.gov/pubmed/3186752
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