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Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa.

We have studied the interaction of the congenitally abnormal type IIA and IIB von Willebrand factor (vWF) molecules, both lacking the larger multimeric forms, with the two vWF binding sites on platelets, the glycoprotein (GP) Ib-IX and GP IIb-IIIa complexes. Variant as well as normal (N) vWF were pu...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: De Marco, L, Mazzucato, M, De Roia, D, Casonato, A, Federici, A B, Girolami, A, Ruggeri, Z M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1990
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2394830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114775
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