Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa.

We have studied the interaction of the congenitally abnormal type IIA and IIB von Willebrand factor (vWF) molecules, both lacking the larger multimeric forms, with the two vWF binding sites on platelets, the glycoprotein (GP) Ib-IX and GP IIb-IIIa complexes. Variant as well as normal (N) vWF were pu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: De Marco, L, Mazzucato, M, De Roia, D, Casonato, A, Federici, A B, Girolami, A, Ruggeri, Z M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2394830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114775
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