Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa.

We have studied the interaction of the congenitally abnormal type IIA and IIB von Willebrand factor (vWF) molecules, both lacking the larger multimeric forms, with the two vWF binding sites on platelets, the glycoprotein (GP) Ib-IX and GP IIb-IIIa complexes. Variant as well as normal (N) vWF were pu...

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Pubblicato in:	J Clin Invest
Autori principali:	De Marco, L, Mazzucato, M, De Roia, D, Casonato, A, Federici, A B, Girolami, A, Ruggeri, Z M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2394830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114775
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