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Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation.

von Willebrand factor (vWF) is necessary for the initial attachment of platelets to exposed subendothelium, particularly under flow conditions like those prevailing in the microcirculation. Little is known about its possible participation in subsequent events leading to formation of platelet thrombi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: De Marco, L, Girolami, A, Russell, S, Ruggeri, Z M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3157702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111816
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