Peptidomimetics of Arg-Phe-NH(2) as Small Molecule Agonists of MAS-Related Gene C (MrgC) Receptors

A series of Arg-Phe-NH2 peptidomimetics containing an Arg mimetic were synthesized and tested as agonists of human MrgX1, rat MrgC, and mouse MrgC11 receptors. As predicted from the previously established species specificity, these peptidomimetics were found to be devoid of MrgX1 agonist activity. I...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Bioorg Med Chem
Main Authors: Hin, Niyada, Alt, Jesse, Zimmermann, Sarah C., Delahanty, Greg, Ferraris, Dana V., Rojas, Camilo, Li, Fengxian, Liu, Qin, Dong, Xinzhong, Slusher, Barbara S., Tsukamoto, Takashi
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254045/
https://ncbi.nlm.nih.gov/pubmed/25288495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.025
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