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Peptidomimetics of Arg-Phe-NH(2) as Small Molecule Agonists of MAS-Related Gene C (MrgC) Receptors

A series of Arg-Phe-NH2 peptidomimetics containing an Arg mimetic were synthesized and tested as agonists of human MrgX1, rat MrgC, and mouse MrgC11 receptors. As predicted from the previously established species specificity, these peptidomimetics were found to be devoid of MrgX1 agonist activity. I...

詳細記述

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書誌詳細
出版年:Bioorg Med Chem
主要な著者: Hin, Niyada, Alt, Jesse, Zimmermann, Sarah C., Delahanty, Greg, Ferraris, Dana V., Rojas, Camilo, Li, Fengxian, Liu, Qin, Dong, Xinzhong, Slusher, Barbara S., Tsukamoto, Takashi
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254045/
https://ncbi.nlm.nih.gov/pubmed/25288495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.025
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