DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA

The Mre11–Rad50–Nbs1 (MRN) complex plays important roles in sensing DNA damage, as well as in resecting and tethering DNA ends, and thus participates in double-strand break repair. An earlier structure of Mre11 bound to a short duplex DNA molecule suggested that each Mre11 in a dimer recognizes one...

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Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Sung, Sihyun, Li, Fuyang, Park, Young Bong, Kim, Jin Seok, Kim, Ae-Kyoung, Song, Ok-kyu, Kim, Jiae, Che, Jun, Lee, Sang Eun, Cho, Yunje
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253529/
https://ncbi.nlm.nih.gov/pubmed/25107472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488299
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