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In vitro evolution of high-titer, virus-like vesicles containing a single structural protein

Self-propagating, infectious, virus-like vesicles (VLVs) are generated when an alphavirus RNA replicon expresses the vesicular stomatitis virus glycoprotein (VSV G) as the only structural protein. The mechanism that generates these VLVs lacking a capsid protein has remained a mystery for over 20 yea...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rose, Nina F., Buonocore, Linda, Schell, John B., Chattopadhyay, Anasuya, Bahl, Kapil, Liu, Xinran, Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250146/
https://ncbi.nlm.nih.gov/pubmed/25385608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414991111
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