Viral vectored granulocyte-macrophage colony stimulating factor inhibits vaccine protection in an SIV challenge model: protection correlates with neutralizing antibody

In a previous vaccine study, we reported significant and apparently sterilizing immunity to high-dose, mucosal, simian immunodeficiency virus (SIV) quasispecies challenge (27). The vaccine consisted of vectors based on vesicular stomatitis virus (VSV) expressing simian immunodeficiency virus (SIV) g...

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Detalhes bibliográficos
Main Authors: Schell, John B., Bahl, Kapil, Rose, Nina F., Buonocore, Linda, Hunter, Meredith, Marx, Preston A., LaBranche, Celia C., Montefiori, David C., Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367070/
https://ncbi.nlm.nih.gov/pubmed/22537983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.04.046
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