Antigenic requirement for Gag in a vaccine that protects against high-dose mucosal challenge with simian immunodeficiency virus

We reported previously on a vaccine approach that conferred apparent sterilizing immunity to SIVsmE660. The vaccine regimen employed a prime-boost using vectors based on recombinant vesicular stomatitis virus (VSV) and an alphavirus replicon expressing either SIV Gag or SIV Env. In the current study...

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Vydáno v:Virology
Hlavní autoři: Schell, John B., Bahl, Kapil, Folta-Stogniew, Ewa, Rose, Nina, Buonocore, Linda, Marx, Preston A., Gambhira, Ratish, Rose, John K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323353/
https://ncbi.nlm.nih.gov/pubmed/25591175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.12.027
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